Beginning here.
Joined Jul 2020
COVID-19
万宗同源，花开数枝，各有所表，欧飞叶美。
Fr.Cryptic transmission of SARS-CoV-2 in Washington State（https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276023/）
SEIR动态建模：https://github.com/blab/ncov-cryptic-transmission
COVID-19
关于筛检试验的报道
《Radical shift in COVID-19 testing needed to reopen schools and businesses, researchers say》https://www.sciencemag.org/news/2020/08/radical-shift-testing-strategy-needed-reopen-schools-and-businesses-researchers-say
扩大检测→筛检而非确证试验（PCR），短期高频重复测量、而非并联试验，单次价格、准确性和耗时都远低于PCR，预估总成本还是很惊人的，但是好过经济停摆。
没有找到文中的模型引文（链接打不开？）
每当放松警惕，就讲讲后遗症，比相约爬山的老梗好使多了。
《From ‘brain fog’ to heart damage, COVID-19’s lingering problems alarm scientists
》By Jennifer Couzin-Frankel
https://www.sciencemag.org/news/2020/07/brain-fog-heart-damage-covid-19-s-lingering-problems-alarm-scientists?utm_campaign=news_daily_2020-07-31&et_rid=687267892&et_cid=3430874
补充brain frog（脑雾）的知识点：Brain fog is a symptom of another medical condition. It’s involves memory problems, a lack of mental clarity, and an inability to focus.
https://www.healthline.com/health/brain-fog#diagnosis
闻香识美人（雾）
《The molecular basis of thioalcohol production in human body odour》
https://www.nature.com/articles/s41598-020-68860-z
外行看个热闹：
1.Introduction and Discussion
第一句Body odour is a characteristic trait of Homo sapiens（体味～智人有什么鬼的关联？）突然想到，通常去我们都会觉得动物园🐒什么的都好臭，动物是不是也这样抗拒人类的体味？——快1/2的“讨论”部分The composition of the modern human axilla is considered unique in composition and diversity relative to other primates. The increasing abundance of Staphylococcus species,can be considered indicative of an evolutionary trajectory toward modern humans. （葡萄球菌物种日益丰富,可以被认为是现代人类进化轨迹的指标。）——（图文并茂提出假设前提）we suggest that thioalcohol production predates the emergence of Homo sapiens as a species.——The emergence of an enzyme present in bacteria found in the human underarm with unique activity to catalyse production of 3M3SH suggests selection pressure for the production of odours over an extended period of evolutionary time. （duang～狐臭是酶的情趣）
2.Method （超纲了，提取一些看得懂的流程吧）
半胱氨酸-硫醇酶（C-T lyase）～PLP
C-S lyase蛋白的克隆、表达和纯化——ShPatB 位点靶向突变——测定体内Cys-Gly-3M3SH生物转化——体外动力学稳态（用 Epoch2 （BioTek） 板读卡器）——吸收光谱分析——确定结构——配体建模（AceDRG）——葡萄球菌spp.核心基因组分析（NCBI）——时间缩放贝叶斯植物遗传学分析（BEAST2.5.2）（一开始看细菌套植物分析法有点怪）
川普听了想流泪
遗憾，这项巴西最新的大型开放性临床试验得出阴性结果：无论羟氯喹（HCQ）是否联合阿奇霉素（azithromycin），15天后接受HCQ与对照组（标准对照）的临床表现均无统计学差异。（此前低样本的动物模型曾点燃一点希望，至此，老药新用停滞不前，中和抗体折戟；新药和疫苗加油啊。）
《Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19》
https://www.nejm.org/doi/full/10.1056/NEJMoa2019014?source=nejmtwitter&medium=organic-social
DOI: 10.1056/NEJMoa2019014
Beginning here.
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